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Ease up is a calming supplement used to help maintain the normal disposition of the horse, allowing for more relaxed behavior. Ingredients Include: L-Taurine, Tryptophan, Magnesium Proteinate, GABA, Thiamine HCL, Distillers Grain DIRECTIONS FOR USE (HORSES): Give 25g daily (1 scoop is approximately 25 grams) Neurotransmitters are chemicals produced by the nerve cells responsible for transmitting signals from one nerve cell (neuron) to another and have many receptor sites in the brain, organs, muscles, digestive, respiratory and olfactory tract that regulate a multitude of processes including emotions. Serotonin and GABA (gamma butyric amino acid) are neurotransmitters important for relaxation, reducing anxiety and improving coping from stressful or new situations such as new competition or training environments, intense workouts, confinement or transport. 90% of Serotonin is produced in the gastrointestinal tract from endocrine cells called enterochromaffin (EC) cell. Serotonin is responsible, not only for improving behaviour, reducing anxiety and having a “calming” effect, but also impacts digestion, appetite and pain management. Studies from the California Institute of Technology (Caltech) in Pasadena have shown that good “gut” microbes will increase serotonin levels which correlates to horses that have good gut health are happier and more relaxed. Serotonin also requires the essential amino acid tryptophan as well as several cofactors such as Vitamins B6, and magnesium to be efficiently produced. Another “calming” neurotransmitter is GABA (gamma-amino butyric acid) made from the amino acids taurine and glutamine. GABA sends chemical messages through the brain and the nervous system and reduces stress by preventing nerve cells (neurons) from becoming over-excited, especially when horses are exposed to new environments, loud noises, and/ or transport. GABA plays an important role in improving coping and response to stress, enabling horses to have better understanding and discernment of new environments and or situations. Ease Up is an excellent “anti-stress” formula containing the “calming” neurotransmitter GABA, as well as tryptophan, and vitamin B6 essential for the production of serotonin. Both GABA and Serotonin will improve relaxation and stress management. Ease Up also contains additional calming nutrients such as magnesium, taurine, thiamine (B1) and inositol (Vitamin B8) which keeps the central nervous system healthy, improving mental focus and relaxation.